Popular Drug Combinations used in Psychiatry

Popular Named Psychiatry Drug Combinations

Here are some well-known, named drug combinations used in psychiatry:

1. California Rocket Fuel

  • Combination: Venlafaxine (SNRI) + Mirtazapine (NaSSA)
  • Indication: Treatment-resistant depression.

2. Dirty Amphetamine

  • Combination: Bupropion (NDRI) + Stimulants (e.g., Methylphenidate or Amphetamine)
  • Indication: ADHD with comorbid depression or fatigue.

3. Symbyax

  • Combination: Fluoxetine (SSRI) + Olanzapine (Atypical Antipsychotic)
  • Indication: Bipolar depression, treatment-resistant major depression.

4. Lithium-Lamictal Combo

  • Combination: Lithium (Mood Stabilizer) + Lamotrigine (Anticonvulsant)
  • Indication: Bipolar disorder, especially bipolar depression.

5. Triple Threat

  • Combination: SSRI or SNRI + Bupropion (NDRI) + Mirtazapine (NaSSA)
  • Indication: Severe, treatment-resistant depression.

6. Aripiprazole Boost

  • Combination: SSRI (e.g., Escitalopram) + Aripiprazole (Atypical Antipsychotic)
  • Indication: Major depressive disorder (adjunct therapy).

These combinations are widely recognized in psychiatric practice for their unique effectiveness in specific conditions or treatment-resistant cases.

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