Pregabalin and Gabapentin Abuse: A Growing Threat Behind the Mask of Pain Relief
š āJust for Nerve Pain, Doctorā¦ā ā But Thereās More Than Meets the Eye
Pregabalin (Lyrica, Nervigesic, Pregaba) and Gabapentin (Gabapin, Neurontin) were developed to treat neuropathic pain, epilepsy, and anxiety. But over the last decade, these so-called āsafeā drugs have quietly become agents of misuseāespecially in Chennaiās pharmacies, clinics, and informal settings.
Originally thought to have low addiction potential, these drugs are now being misused across:
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Pain clinics
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Online pharmacies
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Psychiatric prescriptions with poor follow-up
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Urban communities, even by patients without a history of substance use
ā ļø Why Are These Drugs Misused?
Both pregabalin and gabapentin affect calcium channels in the brain, reducing excitability and creating a sensation of calm, sedation, or even mild euphoria in high doses.
Common reasons people misuse them:
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To self-medicate anxiety or insomnia
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As a ālegal highā when access to opioids or benzodiazepines is restricted
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To potentiate the effects of alcohol, opioids, or tramadol
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Believing they are ānon-addictiveā or āsafeā pain relievers
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After developing tolerance to sleeping pills or antidepressants
š Signs of Pregabalin/Gabapentin Misuse
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Taking higher-than-prescribed doses
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Using without prescriptionāoften bought from multiple pharmacies
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Daytime sedation or emotional blunting
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Memory lapses and poor coordination
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Social withdrawal, irritability, or mood swings
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Combining with other sedatives, opioids, or alcohol
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Strong cravings, and withdrawal symptoms when attempting to stop
š± What Makes This Dangerous?
1. Psychological Dependence
People begin using it for pain or sleepāand later feel they canāt āfunctionā without it.
2. Withdrawal Symptoms
Stopping suddenly can lead to:
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Anxiety, restlessness, sweating
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Insomnia and mood crashes
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Flu-like symptoms
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In severe cases, seizures or rebound pain
3. Neuropsychiatric Effects
Chronic high-dose use can cause:
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Emotional blunting or apathy
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Depersonalization (feeling detached from self)
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Aggression or impulsivity
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In vulnerable individuals: psychosis-like symptoms
4. Risk of Overdose and Death
Especially when combined with:
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Alcohol
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Benzodiazepines (e.g., Clonazepam)
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Opioids (e.g., Tapentadol, Tramadol)
Pregabalin is now a Schedule H1 drug in India, but enforcement remains weak.
š„ How We Manage Pregabalin and Gabapentin Abuse
At Apollo Clinic, Velachery & Tambaram, we provide structured, AIIMS/NDDTC-informed care for individuals struggling with prescription medication misuse.
Our protocol includes:
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Detailed assessment ā dose, duration, co-use, emotional triggers
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Gradual tapering plan ā safe, supervised, and stepwise
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Substitute medications ā for pain or anxiety as needed
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CBT for emotional coping and medication-free functioning
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Sleep recovery therapy and stress management
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Family education and relapse prevention tools
āWe help you move from medication dependence to mental clarity.ā
šØāāļø Who Should Seek Help?
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Anyone using Pregabalin or Gabapentin for more than 4ā6 weeks
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Those taking high doses or multiple tablets per day
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People combining these drugs with alcohol or sedatives
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Individuals feeling foggy, dull, or emotionally flat
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Patients whose ānerve painā or sleep hasnāt improved but the pills continue
š Break Free from Prescription Pill Dependence
It may have started as pain relief. But if itās now controlling your mood, sleep, or energyāitās time to get help.
š Apollo Clinic ā Velachery & Tambaram
š± 8595155808
š www.srinivasaiims.com
āFreedom from pain shouldnāt come at the cost of freedom from yourself.ā
āļø About the Author
Dr. Srinivas Rajkumar T, MBBS, MD (Psychiatry)
Consultant Psychiatrist | Apollo Clinic, Velachery & Tambaram
Trained at AIIMS & NDDTC, Ghaziabad ā Indiaās Apex Centre for Addiction Psychiatry
Dr. Srinivas brings unmatched expertise in managing complex cases of prescription drug dependence, having worked with patients from all over India during his residency at NDDTC. His structured, step-by-step approach helps patients regain control of their lifeāwithout fear, guilt, or confusion.